degV [2019-07-12 09:38:23]

fatty acid binding protein

locus: BSU35480

pI: 5.23

mw: 31.43 kDa

protein length: 281 aa

gene length: 846 bp

function: phosphorylation of fatty acids

product: fatty acid binding protein

essential: no

ec: 3.6.1.1

synonyms: yviA,sacU

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.2|Biosynthesis of lipids] → [category|SW 2.4.2.2|Biosynthesis of phospholipids]

Gene

Coordinates: 3,643,664 → 3,644,509

The protein

Catalyzed reaction/ biological activity

• binds and presents fatty acids for phosphorylation to [protein|5DE73E8005AFFD30EB84696B2C2474899C6D1982|FakA] (based on findings for homologous proteins from Staphylococcus aureus) [pubmed|30429218]

Protein family

• UPF0230 (degV) family (according to Swiss-Prot) PpaX family (according to Swiss-Prot)

Paralogous protein(s)

• [protein|C13F1870B014F8B2C16D9B169F40747DE5B51B85|YitS]

Structure

• [PDB|3FYS]

Expression and Regulation

Operons

• genes: [gene|FB9ABF1FE4EC062C039A62B28A192BAA9B565EEF|degV]
  description: [Pubmed|8412657]

Biological materials

Mutant

• MGNA-A387 (yviA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/387 NBRP B. subtilis, Japan]
• BKE35480 (Δ[gene|FB9ABF1FE4EC062C039A62B28A192BAA9B565EEF|degV]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE35480 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGCTTCGATACCTGCCT, downstream forward: _UP4_TAAGGCCAAATCTCCGTTTT
• BKK35480 (Δ[gene|FB9ABF1FE4EC062C039A62B28A192BAA9B565EEF|degV]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK35480 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAGCTTCGATACCTGCCT, downstream forward: _UP4_TAAGGCCAAATCTCCGTTTT

References

• 19390149,8412657,30429218